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Team Sirius wishes very much strength to all those who fight in her or his way against the Covid-19 virus and its consequences.

Disinfection mean and clean
Industry versus cosmetics
When we mention disinfection, we have to distinguish between industrial disinfection and cosmetic/pharmaceutical disinfection. The regulations for the latter applications are a lot stricter, because they come into contact with the human body.Chemicals meant to harm bacteria could be harmful to human cells for comparable reasons.

Some industrial disinfectants (antisceptics, biocides) also are present in cosmetics. In that case, they have a lower admissable concentration.

Most biocides work on the cell wall of bacteria. Either directly; cell wall damaging, or indirectly; by infering with enzymes needed for cell wall formation. Animal (human) cells do not have cell walls and do not know such enzymes. Sometimes a disinfectant can affect the human cell mémbrane. It is not surprising that health investigations are continuously performed on existing and new antisceptics.

Cleaning versus disinfection
It is not always immediately clear whether a detergent should be preceived as a means to cleaning or disinfection. The difference is important, because a tight legislation exists for disinfectants compared to cleaning products. Important what claims are mentioned on the labels and in the marketing of the end products. Announce that your product keeps surfaces “clean longer” and “removes all bad odours” and the market embraces you. Call your product “hygienic” and sooner or later you will receive a phone call from the National Institute for Public Health and Environmental Affairs.

When the Dutch Law for Crop Protection and Biocides was introduced in the Netherlands, 1600 biocides were presented for registration. The Authorisation Board (CTGB) carried out various checks on the claims of many products. Of the original 1600 biocides only 300 pre-registrations are left. The expectation is that 240 biocides will be allowed onto the Dutch market after July 2011. The CTGB has a good reputation in the rest of the World.

The Sirius Effect
It is a benefit that disinfectants embitter bacteria (and funghi, and sometimes viruses), but a disadvantage that these product snot always distinguish between organisms, such as consumers.

Sirius turns this around: it is a disadvantage that so many disinfectants still need to be tested before being admitted, but an advantage that, apparently, there is a large choice!

Below overview is just a selection from the actual possibilities. You should certainly ask us for advise and alternatives which, in your product, make the difference between clean and hygienic.

And then there are the exotic alternatives like coatings with silver ions and nano-TiO2 which oxidize bacteria in combination with light.

Some products we bring in different forms. Such as the tabletted SPC; a handful of tablets en some water decontaminate large surfaces.

Alcohol does a lot too; in some hand disinfectants, alcohol is the only antisceptic.

Finally, there are scientists who claim that washing with soft soap remives/kills as many bactria as washing with disinfectants. Should you support that school; the raw materials for soft soap can naturally also be obtained with us.

Industrial and home disinfection:

Formalin methanal CAS no: 50-00-0
solution in water of the gas formaldehyde. Formaldehyde is considered carcinogenic. In the EU, products containing more than 0.05% formaldehyde must say so on the label. The maximum level anyway is 0.2%. Still, in some countries, formaldehyde is illegally used a food conservative

CMIT 5-Chloro-2-Methyl-4-Isothiazoline-3-one CAS no: 26172-55-4

MIT 2-Methyl-4-Isothiazoline-3-one CAS no: 2682-20-4
soluble in water and thus usable in (cooling)water systems. Mixes of CMIT/MIT are effective. For people only toxic in high concentrations, but so are acids and alkalines

BIT 1,2-Benzisothiazolin-3-one CAS no: 2634-33-5
Tens of percents of the paints, coatings and adhesives we use contain BIT

OIT 2-n-Octyl-4-isothiazolin-3-one CAS no: 26530-20-1
Wood conservation; biologically degradable, though slowly. Above 500ppm this raw material needs to be dislosed on the label

DCOIT 4,5-Dichloro-N-octyl-3(2H)-isothiazolone CAS no: 64359-81-5
Much use din maritime products; relatively environmentally friendly

Bronopol 2-Bromo-2-nitropropane-1,3-diol CAS no: 52-51-7
widely used in cosmetics at first; now mainly in industrial products. Bronopol facilitates formation of carcinogenic nitrosamines, so in most parts of the world it is not used in cosmetics anymore

SPC Sodium percarbonate CAS no: 15630-89-4
Bleach on basis of oxygen. In water, SPC falls apart in oxygen and calcium carbonate. The oxygen oxidizes micro organisms and is further environmentally friendly. In high concentrations in contact with water a too strong oxidizer and thus dangerous

Chloro dioxide CAS no: 10049-04-4
A typical biocide for swimming-, proces and fishing water. Where chlorine becomes effective only between 20-100ppm, 2-20ppm of chloro dioxide is enough. This gas is supplied dissolved in water 0.5-10g/l
Cosmetic/pharmaceutical disinfection in hand- and face cleansing, Cosmetics, tooth paste:

Natrium pyrithione CAS no: 3811-73-2
Used in shampoos, bath foam, bodycare products; functions at lower pH also as conditioner; at higher pH as thickener

Zink pyrithione CAS no: 13463-41-7
Brother of Natrium pyrithione; Zink pyrithione is an anti dandruff product

Triclosan CAS no: 3380-34-5
in tooth paste (anti-plaque) maximum 0.3% is allowed. Triclosan is not completely broken down in the human body, and forms dioxins. With chlorine in f.e. tapwater, Triclosan reacts to form the carcinogenic chloroform. There are studies claiming Triclosan influences the hormone balance. Recently a European Triclosan factory closed down.

Triclocarban CAS no: 101-20-2
The EU wants to ban this product, which still appears in anti-bacterial soaps. Alternatives are probably already pursued. Triclocarban de-activates testosterone.

Chlorohexidine digluconaat CAS no: 18472-51-0
disinfectant for the eye; partly replaced by parabens

Parabenen, esters van para-hydroxybenzoide zuur (benzoic acid)
antisceptic against funghi, not against bacteria. So parabens are really conserbving products. They can evoke skin- and retracory irritation and allergy

Polyquaternium-1 CAS no: 75345-27-6
Bacteria attract polyquaternium; human cells reject it. An ideal product in for example contactlens cleansing fluid

PCMX Chloroxylenol CAS no: :88-04-0
typical ingredient in anti-bacterial soaps. Unfortunately quite toxic to fish

PCMC Chlorocresol CAS no: 59-50-7
less water soluble variant of PCMX

Benzalkonium chloride CAS no: 8001-54-5
typical disinfectant for detergents, because it also is a cationic surfactant. It thus combines conditioning/softening effects with bacteria inhibition. This explains its application in shampoos and conditioners

Distearyldimoniumchloride CAS no: 107-64-2
as benzalkonium chrloride, but containing linear, olfatic (no benzene) chains

And on the scraped knee: just an ordinary plaster with iodine (CAS no: 7553-56-2).

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